One True Thing

Meryl Streep

Kate Gulden

Renée Zellweger

Ellen Gulden

William Hurt

George Gulden

Tom Everett Scott

Brian Gulden

Lauren Graham

Jules

Nicky Katt

Jordan Belzer

James Eckhouse

District Attorney

Patrick Breen

Mr. Tweedy

Gerrit Graham

Oliver Most

David Byron

Senator Sullivan

Stephen Peabody

Harold

Lizbeth Mackay

Dr. Cohen

Mary Catherine Wright

Clarice

Sloane Shelton

Mrs. Best

Michele Shay

June

Bobo Lewis

Muriel

Marylouise Burke

Louisa

Marcia Jean Kurtz

Marcia

Diana Canova

Diana

John Deyle

Santa / Mayor

Hallee Hirsh

Eight-Year-Old Ellen

Jeffrey Scaperrotta

Four-Year Old Brian

Todd Cerveris

Casey

Anna Carolina Alvim

Nurse Teresa